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SAM-e

DCUpdated April 2026

Product Information

Brand
DC
Form
Tablet or Pill
Servings Per Container
15
Product Type
Non-Nutrient/Non-Botanical
DSLD Entry Date
2021-03-25

Target Groups

VeganVegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

All Ingredients

IngredientAmount% DV
S-Adenosylmethionine400 mg

† Daily Value not established.

Label Statements

Formula re: Contains

All living things contain SAM-e (S-adenosylmethionine). The body makes SAM-e from the amino acid methionine. However, you may not be able to obtain sufficient methionine levels simply by ingesting food. In addition, because of age of other factors, levels of SAM-e can fluctuate or decline. Supplementation with SAM-e is the easiest way to increase intake. SAM-e is involved in over 35 biochemical reactions involving enzymatic transmethylation. The methylation process is the mechanism by which the body rids itself of potentially damaging compounds, synthesizes neurotransmitters, makes components of cartilage, regulates enzyme activity within the cell and maintains the flexibility of cell membranes. Science has been looking into this remarkable supplement nd time after time clinical studies have drawn the same conclusions, SAM-e: Promotes healthy joint function and comfort - Boosts mood and emotional well-being. SAM-e is a revolutionary supplement. Because of its popularity and use, it has received widespread exposure in the press. Information has appeared in newspapers, magazine, on the internet, or simply through word of mouth. Whether you're a first time SAM-e user, or have been a fan for years, you probably have some questions. Please see enclosed insert for more information. A note about our enteric coating: SAM-e is enterically coated sot hat you receive optimal absorption. The enteric coating ensures that the breakdown of SAM-e occurs in the small intestine. Clinical trials indicate that absorption is more efficient in the small intestine rather than in the stomach. In addition, the enteric coating is designed to protect SAM-e from moisture. The lack of an enteric coating should not be harmful to the stomach, and there have been no reported cases tot his effect. However, the enteric coating serves as a protective barrier so that SAM-e can be absorbed where it can provide you with the greatest benefits.

Precautions re: All Other

Caution: You should consult your physician before using SAM-e if you are taking MAO Inhibitors. Individuals affected by bipolar (manic) depression should not take this product.

Precautions re: Children

Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.

Precautions re: Pregnant or Nursing or Prescription Medications

Like all supplements, SAM-e is not intended for use by children and you should consult your physician before using SAM-e if you are pregnant or nursing.

Precautions re: All Other

Discontinue use and consult your physician if gastrointestinal discomfort occurs.

Formulation re: Other

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation re: Does NOT Contain

Gluten free

Seals/Symbols

Quali Pure

Formula re: Contains

S-adenosylmethionine 200 mg

Formulation re: Other

Promotes healthy joint function and comfort Boosts mood and emotional well-being Supports healthy liver function

FDA Statement of Identity

Dietary Supplement

Formulation re: Other

SAM-e was discovered in Italy in 1952 and has been one of Europe's best kept secrets for years. Through extensive testing, SAM-e has been shown to be well tolerated by most. But, perhaps the best news is that SAM-e has been found to be a safe nontoxic supplement for nearly everyone in levels of up to 1,600 mg per day.

Suggested/Recommended/Usage/Directions

Directions: For adults, we recommend taking two (2) tablets daily, preferably on an empty stomach. In order to obtain maximum benefits, SAM-e should be taken at least 30 minutes prior to a meal.

Precautions re: All Other

Tamper Evident: Do not use if imprinted foil seal under cap is broken or missing.

Formulation re: Other

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

Precautions re: Children

Keep out of reach of children.

Formulation re: Vegetarian/Vegan

Suitable for vegetarians/vegans.

Formulation re: Does NOT Contain

Contains no wheat, soy, dairy, egg, fish/shellfish, peanuts/tree nuts.

Formulation re: Other

Made in USA

Supplement Facts Panel

Supplement Facts
Serving Size 2 Tablet(s)
Servings Per Container 15
Amount Per Serving% Daily Value*
S-Adenosylmethionine
400 mg

* Percent Daily Values are based on a 2,000 calorie diet.

† Daily Value not established.

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