Double-Strength SAMe 400 mg

General Statements: All Other Content

Supplementing with SAMe The manufacturing process of SAMe yields two forms, the S,S and R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in our SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

General Statements: All Other Content

SAM-e and Joint Function In clinical trials, SAM-e has been shown to help reduce pain in joints and increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.*

General Statements: All Other Content

SAM-e and Mood and Cognitive Function SAM-e’s ability to boost brain cell methylation facilitates youthful DNA enzymatic actions which may help account for its mood-elevating properties. These enzymatic actions are required for the healthy conversion of neurotransmitters, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body’s antioxidant defense and it helps maintain acetylcholine levels necessary for cognitive function.*

General Statements: All Other Content

SAM-e and Liver Function In order to perform its detoxification role, SAM-e facilitates healthy methylation enzymatic processes and boosts hepatic levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.*

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula re: Contains

Our Double-Strength SAMe 400 contains 400mg of active SAMe in each tablet.

General Statements: All Other Content

Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving.

Storage

Double-Strength SAMe is sealed in blister packs for freshness and stability. Store product in a cool, dry place to ensure maximum quality.

Brand IP Statement(s) re: (c), (TM), (SM)

Science-Based Nutrition

Seals/Symbols

Vegan

FDA Statement of Identity

Dietary Supplement

General Statements: All Other Content

Enhances Mood & Neural Function Promotes Joint Comfort & Mobility Supports Liver Health & Detoxification

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product.

Precautions re: All Other

Individuals diagnosed wit bipolar disease or manic depression should avoid supplementing with SAMe.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not use if pregnant or nursing.

Precautions re: All Other

May cause gastrointestinal discomfort is a small percentage of people.

Formulation re: Does NOT Contain

Gluten Free / Soy Free

Formulation re: Vegetarian/Vegan

Vegan

General: Product/Version Code

YDRB151-1

General Statements: All Other Content

SAM-e (S-Adenosyl Methionine) is derived from the amino acid methionine and ATP (Adenosine Triphosphate). ATP is normally synthesized in the body but may become depleted from sickness and aging. SAM-e is concentrated in the liver and brain and has multiple mechanisms of action in the body. As a major methyl donor, it synthesizes hormones, nucleic acids, proteins, phospholipids, catecholamines, and other neurotransmitters.