Skip to content

SAM-e 400 mg

Jarrow FormulasUpdated April 2026

This product has been discontinued. Label data shown is from the last available version.

OTHER INGREDIENTS
  • Titanium dioxide
  • Magnesium stearate
  • Silicon dioxide

Product Information

Form
Tablet or Pill
Servings Per Container
60
UPC
7 90011 20042 0
Product Type
Non-Nutrient/Non-Botanical
DSLD Entry Date
2015-10-22

Target Groups

VeganVegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

All Ingredients

IngredientAmount% DV
S-Adenosyl Methionine400 mg

† Daily Value not established.

Label Statements

Formula re: Contains

SAM-e S-Adenosyl Methionine 400 FULL POTENCY

Suggested/Recommended/Usage/Directions

USAGE: Take 1 tablet per day on an empty stomach or as directed by your qualified healthcare professional.

Precautions re: Pregnant or Nursing or Prescription Medications

WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product.

Precautions re: All Other

Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAM-e.

Precautions re: Pregnant or Nursing or Prescription Medications

Do not use if pregnant or nursing.

Precautions re: All Other

Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.

Brand IP Statement(s) re: (c), (TM), (SM)

Jarrow Formulas SAM-e 400 is foil blister-packed to maximize stability and safety.

Precautions re: All Other

DO NOT use if outer seal of blister pack is broken.

Formula re: Contains

Full Potency 400 mg SAM-e (net yield) is derived from 800 mg of SAM-e tosylate disulfate.

Suggested/Recommended/Usage/Directions

For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.

Storage

Store in a cool, dry place.

Precautions re: Children

Keep out of the reach of children.

General Statements: All Other Content

NEW HIGHER COUNT In Foil Blister Pack Natural

Formula re: Contains

S-ADENOSYL METHIONINE 400 mg (net yield) SAM-e from 800 mg SAM-e tosylate disulfate Highest Concentration of Active S,S Form

General Statements: All Other Content

Promotes: Joint Strength* Liver Detoxification* Mood and Brain Function* Enteric-Coated Tablets

Formula re: Contains

NET YIELD 400 MG SAM-e

Seals/Symbols

GLUTEN FREE

Seals/Symbols

v vegan

FDA Statement of Identity

Dietary Supplement

Formulation re: Vegetarian/Vegan

Suitable for vegetarians/vegans.

Formulation re: Does NOT Contain

No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

Brand IP Statement(s) re: (c), (TM), (SM)

Superior Nutrition and Formulation

Brand IP Statement(s) re: (c), (TM), (SM)

2015 Jarrow Formulas

Formula re: Contains

Natural SAM-e 400 Jarrow Formulas SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate.

General Statements: All Other Content

SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains More of the Active S,S Form Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.

Brand IP Statement(s) re: (c), (TM), (SM)

Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.

General Statements: All Other Content

SAM-e has been clinically shown to have the following benefits: Joint Strength SAM-e supports the production of healthy connective tissue through transulfuration.* In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-e metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.* Brain Metabolism SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).* Liver SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function, including phase II detoxification.*

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General: Product/Version Code

04415SAM460 PROD # 120042

Supplement Facts Panel

Supplement Facts
Serving Size 1 Tablet(s)
Servings Per Container 60
Amount Per Serving% Daily Value*
S-Adenosyl Methionine
400 mg

* Percent Daily Values are based on a 2,000 calorie diet.

† Daily Value not established.

Buy on Amazon

Similar Products