SAMe 400

Formula re: Contains

Natural SAMe 400 Jarrow Formulas SAMe 400 provides a full 400 mg SAMe (net yield) from 800 mg of SAMe tosylate disulfate. SAMe 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains More of the Active S,S Form Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe.

Formulation re: Other

The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.

Formula re: Contains

Jarrow Formulas SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe, the highest active level available.

Formulation re: Other

SAMe supports: Joint Health SAMe supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate. Brain Metabolism and Mood SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes and precursor to acetylcholine, as well as neurotransmitters such as dopamine, norepinephrine, and serotonin, and has been shown to have a positive effect on mood. Liver Function SAMe metabolism supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s) re: (c), (TM), (SM)

Copyright 2021 Jarrow Formulas

Formula re: Contains

S-Adenosyl Methionine

Formulation re: Other

Full potency

Suggested/Recommended/Usage/Directions

Usage: Take 1 tablet per day on an empty stomach or as directed by your qualified healthcare professional.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAMe. Do not use if pregnant or nursing.

Precautions re: All Other

Do not exceed recommended intake. May cause gastrointestinal upset in some persons. Consult a healthcare professional before using this product if you are trying to conceive, under the age of 18, or have a medical condition; if adverse reactions occur, discontinue use.

Precautions re: Children

Consult a healthcare professional before using this product if you are trying to conceive, under the age of 18, or have a medical condition; if adverse reactions occur, discontinue use.

Precautions re: All Other

Jarrow Formulas SAMe 400 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.

Formula re: Contains

Full Potency 400 mg SAMe (net yield) is derived from 800 mg of SAMe tosylate disulfate.

Suggested/Recommended/Usage/Directions

For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.

Storage

Store in a cool, dry place.

Precautions re: Children

Keep out of the reach of children.

Formula re: Contains

Natural pH-sensitive Food-grade EnteroGuard Coating

General Statements: All Other Content

In foil blister pack

Formula re: Contains

S-Adenosyl Methionine 400 mg (net yield) SAMe from 800 mg SAMe tosylate disulfate Highest concentration of Active S,S Form

Formulation re: Other

Supports: Joint health Brain metabolism and mood Liver function

Formula re: Contains

Enteric-Coated Tablets

FDA Statement of Identity

Dietary Supplement

Formula re: Contains

EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

Formulation re: Does NOT Contain

Gluten free

Formulation re: Vegetarian/Vegan

V Vegan